an Endocrine Society Thematic Issue
Read our special collection of journal articles, published in 2022–2023, focused on immuno-endocrinology! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
In a Perspective article in Journal of the Endocrine Society, Cheung and colleagues argue that a dearth of ICD (International Classification of Diseases) codes for endocrine complications of immune checkpoint inhibitor treatment is impeding research as well as patient care. Kinney and coworkers identify factors associated with electing to be screened for participation in a type 1 diabetes prevention trial, in patients with stage 1 or stage 2 of the disease. Quandt and associates report that a specific HLA type is associated with the development of checkpoint inhibitor-induced hypophysitis.
JCEM Case Reports, Dhanasekaran and coauthors describe marked hypoleptinemia in a case of generalized lipodystrophy resulting from checkpoint inhibitor treatment. Craven and colleagues describe a situation in which human anti-mouse antibodies in an infant ketotic hypoglycemia patient interfered with an insulin immunoassay. Sreedhara and associates report on a patient with T-cell lymphoblastic lymphoma presenting as a pituitary mass.
In Endocrine Reviews, Liu and coauthors describe new formulations of levothyroxine designed to improve treatment of hypothyroidism, which is predominantly autoimmune. Carré and associates review the involvement of Coxsackie virus in triggering immune responses that may underlie type 1 diabetes. Komarla et al. discuss the role of autophagy, a process that is bound up with immunity in multiple ways, in endocrine tumors.
In Endocrinology, Skovsø and coauthors extend reports that reduced insulin gene dosage in β cells protects otherwise susceptible mice from type 1 diabetes, noting that Cre itself also appears to be protective. Sequeira and Bolton discuss the role of neuroendocrine-neuroimmune interactions in the stress response. Carbone and others review current theories about the causes of endometriosis; the immune system is centrally involved in most.
In JCEM, Lui et al. report that COVID19 vaccination is associated with a detectable although clinically insignificant increase in thyroid autoantibody titers. Liu and associates describe how exogenous insulin antibody syndrome can lead to life-threatening hypoglycemia in people with diabetes. And Basolo and colleagues report SARS-CoV-2 infection of testicular cells in a substantial proportion of men who died of COVID19, noting downregulation of genes associated with spermatogenesis—a finding that suggests a possible effect of the virus on male fertility.
Published: October 2023
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, The Journal of Clinical Endocrinology & Metabolism, and JCEM Case Reports so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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